Upstate Active Clinical Trials

Study Title:

NRG-BN009: Phase III Trial of Stereotactic Radiosurgery (SRS) or Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Distant Brain Relapse With Brain Metastasis Velocity ≥4 Brain Metastases/Year

What is the purpose of the study? (in Layman's terms, please describe the study)

This study is being done to answer the following question:

Can we extend your life by using a type of radiation therapy called whole-brain radiation therapy that avoids the hippocampus to preserve memory plus the medication memantine that can decrease the risk of side effects of radiation on thinking and memory, to the usual treatment?

We are doing this study because we want to find out if HA-WBRT and memantine is better or worse than the usual approach for your brain cancer. The usual approach is defined as care most people get for cancer that has spread to the brain and returned in other areas of the brain after receiving SRS.

Upstate Institutional Review Board (IRB) Number:

1720942

Study/Protocol ID:

NRG-BN009

Study Phase:

III

Patient Age Group:

Adults

Principal Investigator:

Michael D Mix, MD

Who is eligible?

You may be eligible to take part in this study if you received stereotactic radiosurgery to treat cancer that spread to your brain, and now the cancer has returned in other areas of the brain. Other inclusion criteria apply. Please contact the CRA for more
information.

What is involved if I participate?

• How long is the study?
  After you finish your treatment, your doctor and study team will watch you for side effects and follow your condition. They will check you every 2 to 3 months for at least 1 year after you start treatment. If you are receiving memantine, your doctor will continue to see you in the clinic as needed.
• Is transportation provided or reimbursed?
  No
• Is parking provided or reimbursed?
  Yes
• What tests and procedures are involved?
  Please contact the CRA for more information.

Where will the study take place?

Upstate Cancer Center

Other Information:

Please contact the CRA for more information.

Who can I contact for more information?

Name: Erin Bingham, CCRP
Phone: 315-464-3603
Email: [email protected]

Return to Previous Page || Search Again