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Molecular Pathology

The Special Procedures Laboratory, in the Division of Anatomic Pathology at SUNY Upstate Medical University is a Joint Commission accredited clinical diagnostic facility which offers a growing menu of molecular testing on solid tumors. The laboratory is currently the only laboratory with NYS approval for a variety of molecular tests. The laboratory performs PCR, RT-PCR, FISH and CISH for adult and pediatric neoplasms including various soft tissue tumors, carcinomas and brain tumors. In addition to serving the Upstate Medical University community we are also a referral laboratory for other hospitals and clinics.

Click on the links below for testing information and specimen requirements:

Shengle Zhang, MD
Medical Director
Dr. Zhang is an Assistant Professor of Pathology and Director of the Special Procedures Laboratory. He completed fellowships in Surgical Pathology at Roswell Park Cancer Center, Buffalo New York and in Molecular Diagnostics at Johns Hopkins Medical Institutions, Baltimore Maryland. Dr. Zhang is board certified in Anatomic and Clinical Pathology.
Christine Fuller, MD
Dr. Fuller is an Associate Professor of Pathology and Assistant Director of the Special Procedures Laboratory. She completed fellowships in Surgical Pathology and Neuropathology at Washington University School of Medicine. Her previous appointment was as Medical Director of the Anatomic Pathology FISH Laboratory at St. Judes Research Hospital, Memphis Tennessee. Dr. Fuller is board certified in Anatomic and Clinical Pathology and Neuropathology.

For questions and additional information, contact:
Shengle Zhang,MD
Phone: (315)464-7131
Fax: (315)464-7130
E-mail: zhangs@upstate.edu
OR Kathleen Sayles
Phone: (315)464-7147
Fax: (315)464-7130
E-mail: saylesk@upstate.edu

To order lab supplies,or for lab results, call client services at (315)464-7147 or fax a request to (315)464-7130

Submitting a Sample

  1. Choose appropriate test(s) from roster of tests available
    Click here for available tests
  2. Fill out the requisition form PDF document
    For help with this form contact:
    Kathleen Sayles
    (315)-464-7147
    saylesk@upstate.edu
  3. Include blocks of formalin fixed paraffin embedded tissue and a copy of the Surgical Pathology report.

Shipping & Handling Information

CLIA # 33D0654590

Specimen Shipping Information

  1. Notify the laboratory in advance of specimen arrival and/or to arrange for specimen pickup (pre-arranged courier pick up available in certain areas) by calling (315)464-7147, (315) 464-7134 or Fax (315)464-7130
  2. The transport of specimens by overnight express courier service is preferred.

Specimen Shipping Address

Upstate Medical University
Dept. of Pathology
WH2106766 Irving Ave.
Syracuse, NY Zip 13210
Attn: Kathleen Sayles

Supplies

To request supplies and prepaid courier air bills call (315)464-7147, Monday - Friday, 8:00 a.m. - 4:30 p.m.

Tests Available (click on test for info)


HER2/neu by FISH

Test Includes: HER2/neu gene amplification by FISH
Indications: Breast cancer to determine prognosis and predict response to therapy
Sample Requirements: Formalin-fixed, paraffin embedded tissue with the invasive tumor component. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday. Results available on Wednesday.
CPT Code: 88365
Fee: $500.00



N-myc by CISH

Test Includes: N-myc gene amplification by CISH
Indications: Neuroblastoma to determine prognosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Wednesday. Results available on Thursday.
CPT Code: 88365
Fee $500.00



1p/19q Deletion by FISH

Test Includes: 1p/19q ratio by FISH
Indications: Oligodendroglioma, to determine prognosis and predict response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $500.00



SYT Break Apart by FISH

Test Includes: SYT gene break apart by FISH
Indications: Synovial sarcoma to facilitate diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $500.00



EWS Break Apart by FISH

Test Includes: EWS gene break apart by FISH
Indications: Ewings sarcoma, DSRCT (Desmoplastic small round cell tumor), Clear cell carcinoma, Extraskeletal myxoid chondrosarcoma, Myxoid/round cell liposarcoma to facilitate diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $500.00



EWS Gene Translocation by RT-PCR

Test Includes: EWS Gene Translocation by RT-PCR
Indications: Ewings sarcoma to facilitate diagnosis
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday. Results available on Thursday.
CPT Code: 83912
Fee $500.00



FKHR Gene Break Apart by FISH

Test Includes: FKHR gene break apart by FISH
Indications: Alveolar rhabdomyosarcoma to facilitate diagnosis
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements:
Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time:
Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $500.00



EGFR Gene Amplification by FISH

Test Includes: EGFR Gene Amplification by FISH
Indications: Non small cell carcinoma of lung to determine prognosis and predict response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
(315)-464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday. Results available on Thursday.
CPT Code: 88365
Fee $500.00
750 East Adams Street
Syracuse, NY 13210-1834
Phone: 315 464-5540
Toll Free: 877 464-5540



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