Structural, Molecular and Systems Biology
Structural, Molecular, and Systems Biology informs and supports research in all of the disease-related pillars. Recent technological advances permit investigators to understand diseases at a molecular and cellular level and to develop targeted treatments. Structural biology, which visualizes the detailed three-dimensional shape of biological macromolecules, has paved the way for understanding genetic diseases that affect protein structure and for targeted drug design. Molecular biology uses the wealth of DNA sequence data now available to understand normal physiology and disease. Systems biology integrates the information from these techniques to describe how biological macromolecules interact in order to understand how organisms respond to disease, environmental stimuli and stresses.
Upstate investigators include nationally recognized experts in all of these fields who are at the forefront of understanding the molecular basis of health and disease.
Upstate Medical University will share a $12.1 million with two other upstate New York institutions as they work to develop a new medical treatment for multiple sclerosis.
Upstate’s Burk Jubelt, MD, professor of neurology, microbiology and immunology, is the project’s principal investigator.