Bioethics, health policy, end-of-life, social responsibility and medical activism
My group seeks to discover new medicines for attention-deficit/hyperactivity disorder (ADHD) and autism based on discoveries in genetics. These two disorders frequently occur together and cause numerous problems for patients and their families. We need new medicines for these disorders because the ones we use now are only partially effective or cannot be used widely because they cause other problems. Importantly, no medicines can currently cure or prevent these disorders. The Faraone Lab searches for genes that cause ADHD and autism and figures out how these genes differ from genes in other children. We then study how these genes work together with networks of other genes in brain cells. By learning how defects in risk genes for ADHD and autism disturb the functioning of these networks, we find new targets for medicines.
Mechanisms of visual perception of 3-D position, motion, color and object shape, investigated by psychophysical methods.
Application of MR molecular imaging in the evaluation of the heart and breast. Clinical evaluation of radiolabelled monoclonal antibody imaging.
Chromosomal DNA replication origins (location, timing and regulation), replication fork integrity and checkpoint regulation, genomic instability and chromosome fragility in both the yeast and human genome
Diabetes; thyroid disease; obesity; pituitary disease; lipid disorders; adrenal diseases; adolescents with diabetes
Biomarkers for Psychosis in Velocardiofacial Syndrome (NIMH Grant)
Child Psychiatric Diagnosis & Treatment by Primary Care Providers