Bioethics, health policy, end-of-life, social responsibility and medical activism
Professor Faraone has been studying attention deficit hyperactivity disorder (ADHD) for three decades. This topic has been of much interest to him because of the disorder’s high prevalence, its association with marked distress and disability in childhood and adulthood and its personal impact on my family. His research has several foci. One line of work seeks to discover new biological pathways that will, eventually, improve the diagnosis and treatment of the disorder. To achieve this goal, he has been coordinating an international network of researchers that has discovered several genes that cause the disorder. He his also conducting in depth studies of the SLC9A9 gene to better understand its functioning and how it’s disruption leads to neurodevelopmental disorders such as ADHD and autism. Because ADHD is also associated with aggressive behavior, substance use disorders and mood/anxiety disorders, Prof Faraone is studying the genetics of these comorbidities along with methods to predict which ADHD youth are at highest risk for these disorders. Results from these studies are disseminated via scientific publications, https://scholar.google.com/citations?user=PtJmhRwAAAAJ, and via http://adhdinadults.com/, for which he is Program Director.
Mechanisms of visual perception of 3-D position, motion, color and object shape, investigated by psychophysical methods.
Application of MR molecular imaging in the evaluation of the heart and breast. Clinical evaluation of radiolabelled monoclonal antibody imaging.
Chromosomal DNA replication origins (location, timing and regulation), replication fork integrity and checkpoint regulation, genomic instability and chromosome fragility in both the yeast and human genome
Diabetes; thyroid disease; obesity; pituitary disease; lipid disorders; adrenal diseases; adolescents with diabetes
Biomarkers for Psychosis in Velocardiofacial Syndrome (NIMH Grant)
Child Psychiatric Diagnosis & Treatment by Primary Care Providers