Calcium (CA4) |
EPIC Test Name
CALCIUMEPIC Code
LAB53Specimen Requirements
plasma | |
---|---|
Minimum Volume: | 0.5 mL |
Collection: | Collect specimens using standard laboratory procedures. |
Transport: | Room Temperature ASAP |
Stability: | Room Temperature: 7 days at 20-25 degrees C Refrigerated: 21 days at 2-8 degrees C Frozen: 8 months at -15 to -25 degrees C |
Container: | LIT_GRN |
Rejection Causes: | Hemolysis, Insufficient Sample Volume |
Methods
Colorimetric assay with endpoint determinationTurnaround Time
Specimen | Turnaround Time | Frequency |
---|---|---|
plasma | Stat: 90 minutes Routine: 4 hours | 24/7 |
Reference Ranges
Colorimetric assay with endpoint determination
Age | All Range | Unit | Critical Values |
---|---|---|---|
0 days up to 11 days | 7.6-10.4 mg/dL | mg/dL | 0-28 days old: <6.5 and >11.0 mg/dL |
11 days up to 3 years | 9.0-11.0 mg/dL | >28 days old: <6.0 and >13.0 mg/dL | |
3 years up to 13 years | 8.8-10.8 mg/dL | ||
13 years up to 19 years | 8.4-10.2 mg/dL | ||
19 years up to 61 years | 8.6-10.0 mg/dL | ||
61 years up to 91 years | 8.8-10.2 mg/dL | ||
91 years up to 999 years | 8.2-9.6 mg/dL |
Clinical Indications
Calcium is an essential mineral required for bone formation and normal function of the body. In the body, about 99 % of the total body calcium is sequestered in the skeletal system and teeth, and the remaining 1 % exists extracellularly and intracellularly. Intracellular calcium plays a role in muscle contraction, hormone secretion as a second messenger, glycogen metabolism, enzyme activity and cell division and others. Extracellularly, calcium plays a role in blood coagulation, enzyme activity and bone mineralization and others. In the circulation, calcium exists in three different fractions, anion-bound, protein-bound and free or ”ionized”, the sum of these three fraction is the total Calcium that is measured in the serum or plasma of patient samples.Performed
Lab |
---|
Chemistry - Downtown |
Chemistry - Community |
Verona Cancer Center |
Interpretative Information
Hypocalcemia is often caused by malfunction of the parathyroid glands, vitamin-D deficiency, chronic renal failure, hyperphosphatemia. Hypocalcemia in adult can cause osteomalacia.Hypercalcemia can be due to increased mobilization of calcium from the skeletal system or increased absorption. Hypercalcemia mainly occurs to patients with primary hyperparathyroidism (pHPT) or bone metastasis of carcinoma of the breast, prostate, thyroid gland, or lung.
CPT
82310LOINC
17861-6References
Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018.Contact Information
Chemistry - Downtown: (315)464-4460Chemistry - Community: (315)492-5531
Verona Cancer Center: (315)473-3859