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March 1, 2013
Doretta Royer 315 464-4833

Upstate researcher receives $549,783 Leukemia & Lymphoma Society Scholar Award

SYRACUSE, N.Y.— Upstate Medical University researcher Golam Mohi, PhD, has been award a Leukemia & Lymphoma Society Scholar Award, totaling $549,783 for a five-year period, beginning July 1. Mohi will use the award to advance his research into a group of blood cancers known as myeloproliferative neoplasms (MPNs). Patients with MPNs are more susceptible to a host of problems, including thrombosis, anemia, bone marrow fibrosis or acute myeloid leukemia.

The award places Mohi among the society’s team of highly qualified independent investigators who have made sustained original contributions in the field of leukemia.

“The Leukemia & Lymphoma Society Scholar Award is usually presented to top medical schools,” said Mohi, an associate professor whose research is funded by the National Institutes of Health. investigator with the Cancer Research Institute at Upstate. “I am very honored and happy to bring this award to Upstate this year.” Mohi is also an investigator with Upstate’s Cancer Research Institute. The award will support his study titled “JAK2 in Hematopoietic Stem Cell Maintenance and Myelorpoliferative Neoplasms.”

Findings from Mohi’s laboratory studies are leading to a better understanding of how a mutation of the a special gene may cause MPNs and would have significant clinical implications in determining therapies for these blood cancers.

Myeloprolifierative neoplasms are caused when bone marrow cells that produce blood cells develop and function abnormally, resulting in the excessive production of one or more of blood cell types. The JAK2 protein tyrosine kinase mediates signals that promote cell growth and survival. The protein is especially important for controlling the production of blood cells from hematopoietic stem cells that are located within the bone marrow and have the potential to develop into all kinds of blood cells including red blood cells, white blood cells, and platelets.

Mohi’s laboratory is studying the molecular and signaling events controlling hematopoietic stem cell function and how these blood cancers originate and develop.

Caption: Golam Mohi, PhD, received a Leukemia & Lymphoma Society Scholar Award to further his studies into myeloproliferative neoplasms.

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