Professor and Interim Chair: Steven Taffet, PhD

Joseph B Domachowske, MD

Joseph B Domachowske, MD
Appointed 06/26/89
5400 Upstate University Hospital - Downtown Campus
750 East Adams Street
Syracuse, NY 13210

315 464-6331

Current Appointments

Hospital Campus

  • Downtown

Clinical Section Affiliations

  • Pediatrics: Infectious Disease

Research Programs and Affiliations

  • Biomedical Sciences Program
  • Pediatrics
  • Research Pillars


Education & Fellowships

  • Fellowship: National Intsitutes of Health, Laboratory of Host Defenses, 1997
  • Residency: SUNY Health Science Center at Syracuse, 1992
  • MD: SUNY Health Science Center at Syracuse, 1989

Clinical Interests

  • Pediatric infectious diseases

Research Interests

  • Pneumovirus pathogenesis.

Specialties & Certification

  • Pediatrics
  • Pediatric Infectious Diseases

Diseases & Conditions Treated

  • Antibiotic-Associated Diarrhea
  • Antibiotic-Resistant Infections
  • Bacterial Meningitis in Children
  • Fever
  • Giardiasis
  • HIV Infection and AIDS
  • Herpes Encephalitis
  • Immune Abnormalities
  • Infections of Bones and Joints
  • Infectious Mononucleosis
  • Infective Endocarditis
  • Pneumonia
  • Shingles
  • Tuberculosis (TB)
  • Viral Infections in Children
  • Viral Meningitis in Children
  • Yeast Infection or Candidiasis


  • Children


  • Infectious Diseases Society of America (IDSA)
  • American Academy of Pediatrics

Current Hospital Privileges

  • Upstate University Hospital

HealthLinkOnAir Radio Interview

10/6/13 Improving immunization rates in low-income populations

7/25/13 The growing incidence of HPV and its connection to oral sex

8/19/12 Whooping cough cases are on the rise

5/6/12 Antibiotic resistance


Link to PubMed External Icon (Opens new window. Close the PubMed window to return to this page.)

Research Abstract

My laboratory program focuses on the molecular interactions between pneumoviruses and pulmonary epithelium. Short term goals include understanding the mechanisms of virus-induced alterations in epithelial cell gene expression. Longer term goals include developing and characterizing specific anti-viral and anti-inflammatory interventions for the treatment of viral bronchiolitis. We study these interactions in vitro, using tissue culture models, and in vivo using our rodent model of pneumovirus infection. Recently, we have also been successful in demonstrating the physiologic significance of results from our model systems in samples obtained from human infants with severe respiratory syncytial virus bronchiolitis.
Clinical Profile Shortcut: http://www.upstate.edu/findadoc/domachoj
Faculty Profile Shortcut: http://www.upstate.edu/faculty/domachoj


Allen E Silverstone, PhD