-Invasive cardiology and cardiovascular imaging,
-Coronary artery disease prevention.
-Endothelial dysfunction in coronary artery disease.
-Lipotoxicity/glucotoxicity and endothelial/myocyte dysfunction in diabetes.
-Clinical and genetic analysis of valve diseases/Strain/strain rate imagine in cardiomyopathy.
Link to PubMed (Opens new window. Close the PubMed window to return to this page.)
Liu K: The Washington Manual, Cardiology Subspecialty Consult. Wolter Kluwer | Lippincott Williams & Wilkins. Chapter 29 (2008):. Diabetes and Cardiovascular Diseases
Roh M, Paterson AJ, Liu K, McAndrew J, et al. Proteolytic processing of TGFα redirects its mitogenic activity: the membrane-anchored form is autocrine, the secreted form is paracrine. Biochim Biophys Acta-Mol Cell Res 2005, 1743 (3):231-242.
Liu K, Paterson AJ, Zhang F, et al. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. J Neurochem. 2004, 89 (4): 1044-1055.
Liu K, Paterson AJ, Konrad RJ, et al. Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone Secretion. Mol Cell Endocrinol. 2002, 194(1-2): 135-146.
Liu K, Paterson AJ, Chin E et al. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death. Proc Natl Acad Sci U S A. 2000, 97(6): 2820-2825.
Liu K, Ou J, Saku K, et al. Efficient nuclear delivery of antisense oligodeoxynucleotides and selective inhibition of CETP expression by apo E peptide in a human CETP-stably transfected CHO cell line. Arterioscler Thromb Vasc Biol. 1999,19:2207-2213.
Konrad RJ, Mikolaenko I, Tolar JF, Liu K, et al.. The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase. Biochem. J. 2001, 356(Pt 1):31-41.
Konrad RJ, Liu K, Kudlow JE. A modified method of islet isolation preserves the ability of pancreatic islets to increase protein O-glycosylation in response to glucose and streptozotocin. Arch. Biochem. Biophys. 2000 Sep 1; 381(1):92-98