Detection, quantification, and characterization of human retro-viruses, testing of antiviral compounds; understanding the biology of sarcomeric protiens.
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Our laboratory''s primary focus is the detection, quantification, and characterization of human retroviruses. Studies also involve the in vitro and in vivo testing of antiviral compounds. A secondary focus is the role of sarcomeric proteins in cardiomyocyte and cancer cell biology.
Walter M. Stadler, Apurva Desai, David Quinn, Ronald Bukowski, B. Poiesz?, C. Kardinal, N. Lewis, A.. Makalinao, Peter Murray, David Quinn, Frank Torti: A Phase I/II Study of GTI-2040 and Capecitabine in Patients with Renal Cell Carcinoma. Cancer Chemotherapy and Pharacology. (in press)
Bernstein ZP, Doughert T, Gollnick S, Schwartz SA, Mahajan SD, Kepner J, Sumlin A, Stewart C, Wallace P, Walder H, and Poiesz B, Photopheresis in HIV-1 infected patients utilizing Benzoporphyrin Derivatives Verteporfin and light. Current HIV Research. 6:152-163, 2008.
Gopaluni S, Perzova R, Abbott L, Farah R, Shrimpton A, Hutchison R, and Poiesz B. CD8+ Cutaneous T-cell lymphoma successfully treated with Bexarotene: a case report and review of the literature. Am J Hematol. 83:744-6, 2008.
Jasti S, Coyle T, Gentile T, Rosales L, and Poiesz B. Rituxamab as an adjunct to plasmapheresis in TTP: a report of 12 cases and review of the literature. J. Clin Apheresis. 23:151-6, 2008.
Thomas A, Perzova R, Abbott L, Benz P, Poiesz MJ, Dube S, Loughran Jr T, and Poiesz BJ. LGL leukemia and HTLV. In press - AIDS RES HUM RETROVIRUSES.
Harold L. Thurston, Sastry Prayaga, Anish Thomas, Victor Guharoy, Syamalima Dube, Bernard J. Poiesz, and Dipak K. Dube. Expression of Nkx2.5 in wild type, cardiac mutant, and thyroxine-induced metamorphosed hearts of the Mexican axolotl. Cardiovascular Toxicology. 9:13-20, 2009.
Esteban E, Poli M, Poiesz B, Ceriani C, Dube S, Guterrez S, Dolcini G, Perez S, Liitzelschwab C, and Juliarena M. Bovine leukemia virus (BLV) proposed control and eradication program by marker assisted breeding of genetically resistant cattle. In "Animal Genetics" (L. Rechi, Ed) NOVA, Hapuppage, NY; 2009.