Student Publications

2010

• George Christophi and Paul T. Massa. Central neuroinvasion and demyelination by inflammatory macrophages following peripheral virus infection is controlled by SHP-1. Viral Immunology 22(6):371-87 (2010).
  
  
• Amber M. Eade et al. Ontogeny of the enhanced fetal-ethanol-induced behavioral and neurophysiologic olfactory response to ethanol odor. Alcoholism: Clinical and Experimental Research 34(2):206-13 (2010).
  
  
• Renee M. Laird and S.M. Hayes. Roles of the Src Tyrosine Kinases Lck and Fyn in regulating gamma delta TCR signal strength. PLoS ONE 5(1): e8899 (2010).
  
  
• David J. Lubin et al. Folding of tetrameric p53: oligomerization and tumorigenic mutations induce misfolding and loss of function. J Mol Biol. 395(4):705-16 (2010).
  
  
• Anna J. Nichols and Eric C. Olson. Reelin Promotes Neuronal Orientation and Dendritogenesis during Preplate Splitting. Cerebral Cortex, in press. [Epub ahead of print]
  
  

2009

• George Christophi et al. Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype. Lab Invest 27 1-18 (2009).
  
  
• George Christophi et al. Interferon-beta Treatment in Multiple Sclerosis Attenuates Inflammatory Gene Expression Through Inducible Activity of the Phosphatase SHP-1. Clinical Immunology 6:24 (2009).
  
  
• George Christophi et al. Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease. J Virol. 83(2):522-39 (2009).
  
  
• Amanda C. Conta, Justin R. Siebert and D.J. Stelzner. Lack of Axonal Sprouting of Spared Propriospinal Fibers Caudal to Spinal Contusion Injury Is Attributed to Chronic Axonopathy. Journal of Neurotrauma 26: 1-19 (2009).
  
  
• Chad A. Corcoran et al. Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains. J Biol Chem. 284(33):21955-70 (2009).
  
  
• Heba Diab et al. Subunit Interactions and Requirements for Inhibition of the Yeast V1-ATPase. J Biol Chem. 84(20):13316-25 (2009).
  
  
• Amber M. Eade et al. The consequence of fetal ethanol exposure and adolescent odor re-exposure on the response to ethanol odor in adolescent and adult rats. Behavioral and Brain Functions 5:3 (2009).
  
  
• Amber M. Eade and Steven L Youngentob. Adolescent ethanol experience alters immediate and long-term behavioral responses to ethanol odor in observer and demonstrator rats. Behavioral and Brain Functions 5:23 (2009).
  
  
• David Fernandez et al. Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol. 182(4):2063-73 (2009).
  
  
• Erik Kish-Trier and S. Wilkens. Domain architecture of the stator complex of the A1A0-ATP synthase from thermoplasma acidophilum. J. Biol. Chem. 284(18):12031-40 (2009).
  
  
• Adem Koksal et al. Dimeric quaternary structure of the prototypical dual specificity phosphatase VH1. J Biol Chem. 284(15):10129-37 (2009).
  
  
• Renee M. Laird and S.M. Hayes. Dynamics of CD3gammaepsilon and CD3deltaepsilon dimer expression during murine T cell development. Mol. Immunol. 47(2-3):582-9 (2009).
  
  
• Renee M. Laird and S.M. Hayes. Profiling of the early transcriptional response of murine gammadelta T cells following TCR stimulation. Mol Immunol. 46(11-12):2429-38 (2009).
  
  
• Sheena Claire Li and P. Kane. The yeast lysosome-like vacuole: endpoint and crossroads. Biochim Biophys Acta 1793(4):650-63 (2009).
  
  
• Ki Lui and Ying Huang. RanGTPase: A key regulator of nucleocytoplasmic trafficking. Journal of Molecular and Cellular Pharmacology. 3:148-156 (2009).
  
  
• Joanne Montalbano et al. Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation. J Biol Chem. 284:18129-42 (2009).
  
  
• Thien D. Nguyen and S.M. Taffet. A model system to study Connexin 43 in the immune system. Mol Immunol 46(15):2938-46 (2009).
  
  
• Adam S. Olia et al. Structural plasticity of the phage P22 tail-needle gp26 probed with Xenon gas. Protein Science 18(3):537-548 (2009).
  
  
• Priscila Y. Sato et al. Loss of Plakophilin-2 Expression Leads to Decreased Sodium Current and Slower Conduction Velocity in Cultured Cardiac Myocytes. Circulation Research 105(6):523-6 (2009).
  
  
• Jesse B. Schallek et al. Stimulus-evoked intrinsic optical signals in the retina: Spatial and temporal characteristics. Investigative Ophthalmology Visual Science 50(10):4865-72 (2009).
  
  
• Jesse B. Schallek et al. Stimulus-evoked intrinsic optical signals in the retina: Pharmacological dissection reveals outer retinal origins. Investigative Ophthalmology Visual Science 50(10):4873-80 (2009).
  
  
• Jeff Ward et al. HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog. 5(10):e1000613 (2009).
  
  
• Jianxin A. Yu et al. Paxillin-Kinase-Linker (PKL) Tyrosine phosphorylation regulates directional cell migration. Mol. Biol. Cell 20:4706-4719 (2009).
  
  
• Jianxin A. Yu et al. The Focal Adhesion: A Network of Molecular Interactions. The Handbook of Cell Signaling, edited by Ralph Bradshaw and Edward Dennis. (2009)
  
  

2008

• Sarah A. Arrington et al. Concurrent administration of zoledronic acid and irradiation leads to improved bone density, biomechanical strength, and microarchitecture in a mouse model of tumor-induced osteolysis. J. Surg. Oncol. 97(3):284-90 (2008).
  
  
• Prabal Banerjee et al. Human T-cell lymphotropic virus type 1 infection of CD34+ hematopoietic progenitor cells induces cell cycle arrest by modulation of p21(cip1/waf1) and survivin. Stem Cells 26(12):3047-58 (2008).
  
  
• Tania Das Banerjee et al. A Comparison of Molecular Alterations in Environmental and Genetic Rat Models of ADHD: a pilot study. American Journal of Medical Genetics 147B(8):1554-63 (2008).
  
  
• George Christophi et al. Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. J Neurochem. 91(6):1439-49 (2008).
  
  
• George Christophi et al. SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients. Lab Invest. 88(3):243-55 (2008).
  
  
• Amanda C. Conta and D.J. Stelzner. Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. Spinal Cord 46(1):39-44 (2008).
  
  
• Chad Corcoran et al. Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies. Molecular Cancer Research 6(5):795-807 (2008).
  
  
• Miriam L. Donohue et al. Pulse-Train Stimulation for Detecting Medial Malpositioning of Thoracic Pedicle Screws. Spine 33 (12): E378-E385 (2008).
  
  
• David Fernandez and A. Perl. Metabolic control of T cell activation and death in SLE. Autoimmun Rev. 8(3):184-9 (2008).
  
  
• Jason A. Horton et al. Ontogeny of skeletal maturation in the juvenile rat. The Anatomical Record 291(3):283-92 (2008).
  
  
• Chad Hudson et al. Induction of IL-33 expression and activity in central nervous system glia. J Leukoc Biol. 84(3):631-43 (2008).
  
  
• Katherine A. Kaproth-Joslin et al. Phospholipase Cd1 Regulates Cell Proliferation and Cell Cycle Progression from G1 to S Phase by Control of Cyclin E/Cdk2 Activity. Biochem J 415:439-448 (2008).
  
  
• Erik Kish-Trier et al. The Stator Complex of the A(1)A(0)-ATP Synthase-Structural Characterization of the E and H Subunits. J Mol Biol 375(3):673-85 (2008).
  
  
• Shelley Kummer et al. Induction of human host cell apoptosis by Trichomonas vaginalis cysteine proteases is modulated by parasite exposure to iron. Microbial pathogenesis 44(3):197-203 (2008).
  
  
• Rebecca Lewandowski et al. RXP-E: a connexin43-binding peptide that prevents action potential propagation block. Circulation Research 103(5):519-26 (2008).
  
  
• Amanda Lindke et al. Generation and use of primary rat cultures for studies of the effects of ethanol. Methods in Molecular Biology 447:125-36 (2008).
  
  
• Gregory Mitrousis et al. Molecular basis for the recognition of snurportin 1 by importin beta. J Biol Chem. 283(12):7877-84 (2008).
  
  
• Anna Nichols et al. Comparison of slow and fast neocortical neuron migration using a new in vitro model. BMC Neurosci. 9:50, 2008.
  
  
• Adam S. Olia and G. Cingolani. A shifty stop for a hairy tail. Mol. Microbiol. 70(3):549-53, 2008.
  
  
• Danielle A. Sliter et al. Mass Spectrometric Analysis of Type 1 Inositol 1,4,5-trisphosphate Receptor Ubiquitination. Journal of Biological Chemistry 283(51):35319-28, 2008.
  
  
• Rebecca M Smith et al. Nondestructive Optical Determination of Fiber Organization in Intact Myocardial Wall. Microsc Res Tech. 71:510-6 (2008).
  
  
• Margaret M. Stratton, Diana. M. Mitrea and S.N. Loh. A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding. ACS Chem. Biol. 3:723?732 (2008).
  
  
• Jeff Ward and Edward Barker. Role of natural killer cells in HIV pathogenesis. Curr HIV/AIDS Rep. 5(1):44-50 (2008 ).
  
  

2007

• Melissa Andrews and D. Stelzner. Evaluation of olfactory ensheathing and schwann cells after implantation into a dorsal injury of adult rat spinal cord. J Neurotrauma. 11:1773-92 (2007).
  
  
• Prabal Banerjee et al. Pro-inflammatory Cytokine Gene Induction by HTLV 1 and HTLV-2 Tax in Primary Human Glial Cells. Journal of Virology 81(4):1690-1700 (2007).
  
  
• Prabal Banerjee et al. Human T-Cell Leukemia Virus Type 1 (HTLV-1) p12I Down-Modulates ICAM-1 and -2 and Reduces Adherence of Natural Killer Cells, Thereby Protecting HTLV-1-Infected Primary CD4+ T Cells from Autologous Natural Killer Cell-Mediated Cytotoxicity despite the Reduction of Major Histocompatibility Complex Class I Molecules on Infected Cells. Journal of Virology 81(18): 9707-9717 (2007).
  
  
• Tania D. Banerjee et al. Environmental Risk Factors for Attention Deficit Hyperactivity Disorder. Acta Pediatrica 96:1269-1274 (2007).
  
  
• Blaine T. Bettinger et al. Requirement for the polarisome and formin function in Ssk2p-mediated actin recovery from osmotic stress in Saccharomyces cerevisiae. Genetics 175(4):1637-48 (2007).
  
  
• Marla B. Bruns and M.W. Miller. Neurotrophin ligand-receptor systems in somatosensory cortex of adult rat are affected by repeated episodes of ethanol. Exp Neurol. 204(2):680-92 (2007).
  
  
• Marla B. Bruns and M.W. Miller. Functional nerve growth factor and trkA autocrine/paracrine circuits in adult rat cortex are revealed by episodic ethanol exposure and withdrawal. J Neurochem. 100(5):1155-68 (2007).
  
  
• James S. Butler and S.N. Loh. Zn2+-dependent misfolding of the p53 DNA binding domain. Biochemistry 46(10):2630-9 (2007).
  
  
• Michael G. Clark and D.C. Amberg. Biochemical and Genetic Analyses Provide Insight Into the Structural and Mechanistic Properties of Actin Filament Disassembly by the Aip1p Cofilin Complex in Saccharomyces cerevisiae. Genetics 176(3):1527-39 (2007).
  
  
• Thomas A. Cutler and S.N. Loh. Thermodynamic analysis of an antagonistic folding-unfolding equilibrium between two protein domains. J Mol Biol. 371(2):308-16 (2007).
  
  
• Charles Danko et al. Bioinformatic identification of novel putative photoreceptor specific cis-elements. BMC Informatics 8:407 (2007).
  
  
• Michelle E. Farah and D.C. Amberg. Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast. Molecular Biology of the Cell 18(4):1359-65 (2007).
  
  
• Christopher Griffith et al. An oncolytic mutant of herpes simplex virus type-1 in which replication is governed by a promoter/enhancer of human papillomavirus type-16. Cancer Gene Therapy 14(12):985-93 (2007).
  
  
• Changying Jiang et al. Mutations that decrease DNA binding of the processivity factor of the herpes simplex DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease fidelity of DNA replication. Journal of Virology 81(7):3495-502 (2007).
  
  
• Changying Jiang et al. Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. Journal of Virology 81(21):12077-9 (2007).
  
  
• Kideok Jin et al. The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer. Cancer Res 67(15):7247-55 (2007).
  
  
• Rosy Joshi-Mukherjee et al. Evidence for the presence of a free C-terminal fragment of Cx43 in cultured cells. Cell Communication and Adhesion 14:75-84 (2007).
  
  
• Viviana Munoz et al. Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. Heart Rhythm 4(4):487-96 (2007).
  
  
• Joanne Montalbano et al. RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer. The Journal of Biological Chemistry 282(52):37640-9 (2007).
  
  
• Viviana Munoz et al. Adenoviral expression of IKs contributes to wavebreak and fibrillatory conduction in neonatal rat ventricular cardiomyocyte monolayers. Circulation Research 101(5):475-83 (2007).
  
  
• Sami F. Noujaim et al. Up-regulation of the inward rectifier K+ current (IK1) in the mouse heart accelerates and stabilizes rotors. J Physiol 578(Pt1):315-26 (2007).
  
  
• Sami F. Noujaim et al. Universal scaling law of electrical turbulence in the mammalian heart. Proc Natl Acad Sci USA 104(52):20985-9 (2007).
  
  
• Adam Olia et al. Structure of Phage P22 Cell Envelope Penetrating Needle. Nature Structural and Molecular Biology, in press.
  
  
• Adam Olia et al. Role of Gene 10 Protein in the Hierarchical Assembly of the Bacteriophage P22 Portal Vertex Structure. Biochemistry 46(30):8776-8784 (2007).
  
  
• Eva M. Oxford et al. Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Heart Rhythm 4(9):1196-205 (2007).
  
  
• Eva M. Oxford et al. Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells. Circ Res. 101(7):703-11 (2007).
  
  
• Margaret M.P. Pearce et al. SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells. Journal of Biological Chemistry 82:20104-15 (2007).
  
  
• Karsten A. Pilones et al. Prenatal HgCl2 Exposure Alters Fetal Cell Phenotypes. Journal of Immunotoxicology 4(4):295-301 (2007).
  
  
• Rong Rong et al. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene 26(55):7700-8 (2007).
  
  
• Matthew D. Soulsby and R.J. Wojcikiewicz. Calcium mobilization via type III inositol 1,4,5-trisphosphate receptors is not altered by PKA-mediated phosphorylation of serines 916, 934, and 1832. Cell Calcium (3):261-70 (2007).
  
  
• David A. Tumbarello and C.E. Turner. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. J. Cell Physiol 211:736-747 (2007).
  
  
• Melinda J. Tyler and D.A. Cameron. Cellular pattern formation during retinal regeneration: A role for homotypic control of cell fate acquisition. Vision Research 47:501-511 (2007).
  
  
• Jeffrey Ward et al. HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Blood 110:1207-1214 (2007).
  
  
• Patrick Yurco and D.A. Cameron. Cellular correlates of proneural and Notch-Delta gene expression in the regenerating zebrafish retina. Visual Neuroscience 24: 437-43 (2007).
  
  
• Heidi J. Zapata et al. Varicella-zoster virus infection of human fibroblast cells activates the c-Jun N-terminal kinase pathway. Journal of Virology 81(2):977-90 (2007).