- Blair Calancie, PhD
CNS plasticity after trauma; intraoiperative electrophysiology.
- Peter Calvert, PhD
Molecular mechanisms of protein transport and localization in retinal neurons; mechanisms of retinal degenerative diseases
- Gary Chan, PhD
Human cytomegalovirus pathogenesis and persistence.
- Xin Jie Chen, PhD
Mitochondrial biogenesis and inheritance, aging and aging-related degenerative diseases.
- Michael Cosgrove, PhD
Epigenetic regulation of chromatin, Mixed Lineage Leukemia, structural biology, enzymology.
- Richard Cross, PhD
Bioenergetics, enzymology, structural biology, membrane protein function
- Timothy Damron, MD
Radioprotectant strategies: pediatric growth plate. Treatment of Fractures in Pathology Bone, Reconstructive Alternatives: Limb-Sparing Sarcoma Surgery, Genetics of Pagetoid Osteosarcoma
- Eric Deshaies, MD
Neuroprotective strategies following subarachnoid hemorrhage, Cerebrospinal fluid proteomics, Cerebral aneurysm genetics, Ischemic stroke
- Joseph Domachowske, MD
- Dipak Dube, PhD
Molecular mechanism of cardiac myofibrillogenesis in vertebrates.
- Thomas Duncan, PhD
Bioenergetics, enzymology, structural biology, membrane protein function.
- Timothy Endy, MD, MPH
Understanding the epidemiology and pathogenesis of viral hemorrhagic and encephalitic arboviruses and host-vector interactions.
- Stephen Faraone, PhD
Psych. Genetics; ADHD and BP Disorder; Endophenotype. For more detail, see CV
- Bart Farell, PhD
Mechanisms of visual perception of 3-D position, motion, color and object shape, investigated by psychophysical methods.
- Wenyi Feng, PhD
Chromosomal DNA replication origins (location, timing and regulation), replication fork integrity and checkpoint regulation, genomic instability and chromosome fragility in both the yeast and human genome
- Eileen Friedman, PhD
The role of the kinase Mirk/dyrk1B in solid tumors
- Jerrie Gavalchin, PhD
Regulation of pathogenic antibody production in autoimmune glomerulonephritis; Cell-surface receptors for retroviruses
- Debashis Ghosh, MSc, PhD
Structure and function of enzymes in estrogen and androgen biosynthesis; rational design of enzyme modulators in hormonal breast and prostate cancers; characterization of interphotoreceptor retinol binding proteins.
- Stephen Glatt, PhD
Psychiatric Genetic Epidemiology & Neurobiology
- Steven Goodman, PhD
Proteomic assessment of sickle cell severity.
- Steven Hanes, PhD
Gene expression in development and disease, RNA pol II regulation, homeobox genes, prolyl isomerases
- Sandra Hayes, PhD
Roles of B lymphoid kinase (Blk) in lymphocyte development and activation as well as in preventing autoimmunity
- George Holz, PhD
Drug development for the treatment of type 2 diabetes mellitus.
- Brian Howell, PhD
The signal transduction events that regulate the functional organization of neurons in the brain, and the phenotypes caused by defects in the genes that encode these signaling molecules.
- Huaiyu Hu, PhD
Molecular studies of brain malformations.
- Ying Huang, MD, PhD
Oncogenic signaling in cellular transformation and apoptosis; tumor suppressor genes.
- Bihchen Hwang, DDS, PhD
DNA replication of herpes viruses.
- Burk Jubelt, MD
CNS acute and chronic polio- and entero-virus infections; Growth factors for Post-Polio Syndrome; Treatment of Multiple Sclerosis; Amyotrophic Lateral Sclerosis (ALS) Motor Neuron Gene Expression
- Patricia Kane, PhD
Professor and Chair
Vacuolar H+ATPases (structure, function, assembly and regulation), cellular pH homeostasis, cellular stress responses, protein sorting, genomics, yeast as a model system
- Wendy Kates, PhD
Anatomic and functional imaging investigations of neurodevelopment in individuals with genetic or psychiatric disorders
- William Kerr, PhD
Transplant immunology and stem cell biology.
- Dilip Kittur, MD, ScD, FACS
Xenotransplantation, Endothelial cell dysfunction, Use of herbal products in transplant biology
- Barry Knox, PhD
Professor and Chair
Visual transduction, Gene Expression, Membrane proteins
- Leszek Kotula, MD/PhD
Cancer biology, cell signaling, the role of actin cytoskeleton in tumor progression, mouse models of cancer
- Mira Krendel, PhD
Physiological functions of myosin motors and their roles in diabetic kidney disease and cancer
- Andrzej Krol, PhD
Advanced tomographic reconstruction in PET and SPECT. Breast cancer detection and imaging using molecular, MR and x-ray imaging. Nonrigid multimodality breast image registration and fusion. Advanced breast cancer lumpectomy. Ultrafast laser-based x-ray source for biomedical imaging. Advanced tomographic reconstruction in cone-beam micro-CT.
- Stewart Loh, PhD
Protein engineering, design, and folding
- Hong Lu, PhD
Gene regulation during liver development and carcinogenesis
Drug metabolism, liver protection, cancer chemoprevention, and cancer therapy
- Juntao Luo, PhD
Nanomedicine, drug delivery, cancer imaging and cancer treatment; gene delivery and gene therapy, protein/peptide delivery. biomaterials in tissue engineering; combinatorial chemistry and drug discovery; High throughput screening; microarrays.
- Kenneth Mann, PhD
Micro-mechanics of implant interfaces; damage evolution of joint replacements and biomaterials; in vivo models of tumor osteolysis and prediction of fracture risk; general orthopedic biomechanics.
- Bryan Margulies, MS, PhD
- Mesenchymal Stem Cell Biology
- Cell Migration and Cell Fate Choices
- Endochondral Bone Growth
- Orthopedic Tumor
- Paul Massa, PhD
Regulation of innate immune responses to viruses.
- Russell Matthews, PhD
Role of glycoproteins in oncogenesis and brain development
- Frank Middleton, PhD
Molecular basis of cortical-basal ganglia and cortical-cerebellar circuit formation and dysfunction in neurological and psychiatric disease.
- David Mitchell, PhD
Regulation of ciliary dynein activity and assembly, and the role of the central pair complex in ciliary motility regulation.
- Jennifer Moffat, PhD
Varicella zoster pathogenesis.
- Golam Mohi, PhD
Associate ProfessorStem cell biology, cell signaling, hematopoiesis and blood cancer
- Mehdi Mollapour, PhD
Post-translational regulation of the Hsp90 molecular chaperone machinery in cancer
- Brad Motter, PhD
Visual Neurophysiology; Visual Attention; Visual Search Behavior
- Christopher Neville, PT, PhD
- Megan Oest, PhD
Orthopedic tissue engineering; angiogenesis & graft/implant viability; fetal basis of adult disease; intrauterine stem cell programming.
- Eric Olson, PhD
Cellular and molecular mechanisms of cerebral cortex development.
- Donna Osterhout, PhD
Biology of oligodendroglia and myelin formation during development, remyelination and repair in spinal cord injury and MS"
- Andras Perl, MD, PhD
Genes and Viruses Predisposing to Autoimmunity, Genetics, Apoptosis, Endogenous Retroviruses, Transaldolase
- Arkadii Perzov, PhD
Biophysical mechanisms of cardiac arrhythmias; fluorescence imaging.
- Francesca Pignoni, PhD
Associate ProfessorNeurogenesis; Retinal Progenitor Cells Specification and Proliferation; Genetic Control of Stem Cell Identity and Maintenance; Disease Genes Analysis in Drosophila
- Thomas Poole, PhD
Vascular development and the alignment of growing nerves and blood vessels in quail and zebrafish embryos.
- Dawn Post, PhD
Cancer treatments. My lab is currently investigating two different cancer therapy approaches: (1) oncolytic viruses and (2) inhibitors of the EGFR/Her pathway.
- Michael Princiotta, PhD
Antigen processing and presentation; Cytotoxic T lymphocyte response to viral and bacterial infections
- David Pruyne, PhD
Biochemistry and cell biology of formins as actin cytoskeleton organizers, using Caenorhabditis elegans as a model system.
- Jean Sanger, PhD
Analysis of the assembly of the actin/myosin cytoskeleton in muscle and non-muscle cells.
- Joseph Sanger, PhD
Professor and Chair
Cellular analysis of the formation of myofibrils, stress fibers, and cleavage furrows in living cells.
- Mark Schmitt, PhD
Ribonucleoprotein assembly and biogenesis; mitochondrial RNA import, mRNA degradation, cell cycle control
- M Saeed Sheikh, MD, PhD
Apoptotic signal transduction and cancer biology.
- Edward Shillitoe, PhD
Gene therapy for cancer; Bacterial causes of obesity, diabetes and periodontal disease
- Allen Silverstone, PhD
How dioxins and estrogens and estrogenic compounds affect the immune system.
- Vladimir Sirotkin, PhD
Mechanisms of the actin cytoskeleton assembly and role of myosin-1 during endocytosis in fission yeast.
- Joseph Spadaro, PhD
Electromagnetic and mechanical regulation of bone physiology;
Bone density and osteoporosis;
Skeletal irradiation effects;
- Steven Taffet, PhD
Regulation of intercellular communication in the heart, gene expression during macrophage activation
- Daniel Tso, PhD
Neuronal mechanisms of visual perception, studied through physiological, anatomical and functional imaging techniques.
- Christopher Turner, PhD
Regulation of cell migration by focal adhesion adapter proteins and their role in cancer cell metastasis.
- Mary Lou Vallano, PhD
Neuronal survival and development.
- Richard Veenstra, PhD
Regulation of connexin-specific-gap-junctions; gap junction channel biophysics.
- Andrea Viczian, PhD
Mammalian retinal stem cells formation; molecular mechanism of retinal cell fate decisions; using cell replacement therapy to heal the blinded eye.
- Stephan Wilkens, PhD
Structure and Mechanism of Membrane Bound Transport Proteins
- Gary Winslow, PhD
Host defense against intracellular pathogens, B cell responses, immunological memory
- Richard JH Wojcikiewicz, PhD
Professor and Interim Chair
Intracellular signaling via InsP3 receptors and their regulation by the ubiquitin/proteasome pathway and Bcl-2 family proteins.
- Yunlei Yang, MD, PhD
Deciphering and manipulating the cellular signaling circuits for feeding behaviors using approaches including electrophysiology, pharmacogenetics and optogenetics.
- Steven Youngentob, PhD
In utero ethanol and nicotine exposures and chemsensory systems plasticity, olfactory biomarkers of ADHD, olfactory signal transduction, peripheral and central mechanisms of odorant quality coding.
- Li-Ru Zhao, PhD
Brain plasticity, Brain repair, stroke, Alzheimer’s disease, CADASIL, Traumatic brain injury, Live brain imaging, Stem cell biology and therapy, Cell signaling, Cell-cell interaction.
- Sijun Zhu, MD, PhD
Genetic mechanisms of Drosophila neural stem cell self-renewal and specification
- Michael Zuber, PhD
The molecular basis of retinal stem cell formation; regulating retinal stem/progenitor cell proliferation; using retinal stem/progenitor cells to heal the injured or degenerating retina.