Members and Collaborators

Rosemary Rochford, PhD

Rosemary Rochford, PhD
Appointed 09/02/03
2120 Weiskotten Hall
766 Irving Ave.
Syracuse, NY 13210

315 464-5453

Current Appointments

Hospital Campus

  • Downtown

Research Programs and Affiliations

  • Biomedical Sciences Program
  • Cancer Research Institute
  • Microbiology and Immunology
  • Research Pillars

Education & Fellowships

  • PhD: University of California at Irvine, 1989

Research Interests

  • Etiology of viral-associated malignancies, gammaherpesvirus pathogenesis.

HealthLinkOnAir Radio Interview

11/21/13 Unveiling Upstates new Neuroscience Research Building

5/15/13 How will the NIH grant funding sequester affect local research?

3/13/13 Challenges in Cancer Research in Africa

4/29/12 Bird flu virus controversy

Publications

Link to PubMed External Icon (Opens new window. Close the PubMed window to return to this page.)

Research Abstract

Infection with Epstein-Barr virus (EBV) is associated with a number of malignancies including endemic Burkitt's lymphoma (eBL), the most common childhood cancer in sub-Saharan Africa. The current research in my laboratory is directed towards three main areas of investigation. First, we have established a field research project based in Kisumu, Kenya to understand the how the interaction of co-factors including holoendemic malaria in the context of early primary infection with EBV lead to the emergence of eBL. Second, we are utilizing infection of mice with the murine gammaherpesvirus-68 (MHV-68) to examine early events in gammaherpesvirus pathogenesis as well as to model virus-parasite interactions. Finally, we are developing mechanism-based therapies for the treatment of BL and other AIDS-associated non-Hodgkin's lymphomas that address the unique needs in resource-poor settings using a preclincal model. In this preclinical model, SCID mice are engrafted with BL lines that have been in short-term culture and tagged with luciferase. We are using bioluminescent imaging to monitor tumor growth and response to treatment and to determine whether targeting of angiogenesis by adopting a metronomic schedule of therapy can induce remission and reduce toxicity.

Faculty Profile Shortcut: http://www.upstate.edu/faculty/rochforr

Emeritus Faculty

Syracuse University

Cornell University

  • Hening Lin, Ph.D.
    Assistant Professor
    Chemistry
  • Eloy Rodriguez, Ph.D. External Icon
    James A Perkins Professor
    Department of Plant Biology

Clarkson University

SUNY Binghamton University

SUNY Buffalo State College

SUNY ESF

SUNY Downstate University

Wadsworth Center

Technion—Israel Institute of Technology

  • Yuval Shaked, Ph.D.
    Senior Lecturer
    Molecular Pharmacology

Veterans Hospital, Syracuse

  • William Marx, DO, FACS
    Chief of Staff
    Veterans Hospital

School of Medicine and Biomedical Sciences, SUNY University at Buffalo

Other Organizations

  • Ben-Zion Levi, Ph.D. External Icon
    Professor, Faculty Dean
    Department of Biotechnology and Food Engineering
    Technion—Israel Institute of Technology
    Haifa, Israel
  • Cheng-Chang Lu, Ph.D.
    National Cheng Kung University, Taiwan
  • Tak-Wah Wong, Ph.D.
    National Cheng Kung University, Taiwan
  • Li-Wha Wu, Ph.D.
    National Cheng Kung University, Taiwan