Community General Hospital opened is doors on January 1, 1963, after a decade of community planning, fundraising and construction. Over $7 million had been donated, representing over 48,000 pledges from businesses, foundations and individuals. Since then, the hospital has pursued and achieved many successes and increased its services dramatically in an effort to continually improve patient care.
- In 1964, Community Hospital merged with the 69-year-old Syracuse General Hospital. The resulting institution was named Community General Hospital of Greater Syracuse. The Onondaga Hill location absorbed both staff and equipment from both former institutions.
- Special services have been added over the years. In 1975, Community General Hospital opened Central New York's first one-day surgery service. In 1985, Community General Hospital completed construction of a state-of-the-art Intensive Care Unit, and the Sleep Center opened in 1987.
- In 1992, Community General Hospital opened an Outpatient Physical Therapy and Occupational Therapy service located on Velasko Road, and an Industrial Rehabilitation service was established at the same location in 1994.
- A number of state-approved Certificate of Need modernization projects were completed in 1995 to expand and modernize hospital services. These included renovated and expanded emergency and laboratory services, modernized patient rooms, and state-of-the-art ambulatory and inpatient surgery suites.
- CGH facilities and equipment continue to advance as medical technology progresses. Frequent inspections by New York State authorities show consistent compliance with stringent standards for quality and performance. Community General Hospital is accredited by the nationwide Joint Commission on the Accreditation of Healthcare Organizations.
- In 2011, Upstate Medical University acquired Community General Hospital, and was renamed "Upstate University Hospital at Community Campus" on July 7, 2011.