Joseph Domachowske profile picture
315 464-7588

Joseph Domachowske, MD

5400 Upstate University Hospital
750 East Adams Street
Syracuse, NY 13210
Joseph Domachowske's email address generated as an image

CURRENT APPOINTMENTS

Professor of Pediatrics

SPECIALTIES

Pediatric Infectious Diseases
Pediatrics

LANGUAGES

English
Spanish

PATIENT TYPE

Children

RESEARCH PROGRAMS AND AFFILIATIONS

Biomedical Sciences Program
Pediatrics

RESEARCH INTERESTS

Pneumovirus pathogenesis.

ASSOCIATIONS / MEMBERSHIPS

American Academy of Pediatrics, Vice President District 2 Chapter 1
American Society of Tropical Medicine and Hygeine (ASTMH)
Infectious Diseases Society of America (IDSA)
Onondaga County Pediatric Society

EDUCATION

Fellowship: National Intsitutes of Health, Laboratory of Host Defenses, 1997
Residency: SUNY Health Science Center at Syracuse, 1992
MD: SUNY Health Science Center at Syracuse, 1989

RESEARCH ABSTRACT

My laboratory program focuses on the molecular interactions between pneumoviruses and pulmonary epithelium. Short term goals include understanding the mechanisms of virus-induced alterations in epithelial cell gene expression. Longer term goals include developing and characterizing specific anti-viral and anti-inflammatory interventions for the treatment of viral bronchiolitis. We study these interactions in vitro, using tissue culture models, and in vivo using our rodent model of pneumovirus infection. Recently, we have also been successful in demonstrating the physiologic significance of results from our model systems in samples obtained from human infants with severe respiratory syncytial virus bronchiolitis.

PUBLICATIONS

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