Recent Publications

Myosin 1e is a component of the invadosome core that contributes to regulation of invadosome dynamics.
Ouderkirk JL, Krendel M.
Exp Cell Res. 2014 Apr 1;322(2):265-76.

Visualization of cytoskeletal dynamics in podocytes using adenoviral vectors.
Bi J, Pellenz CD, Krendel M.
Cytoskeleton. 2014 Mar;71(3):145-56.

Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes.
Bi J, Chase SE, Pellenz CD, Kurihara H, Fanning AS, Krendel M.
Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F532-44.

Podocyte-specific knockout of myosin 1e disrupts glomerular filtration.
Chase SE, Encina CV, Stolzenburg LR, Tatum AH, Holzman LB, Krendel M.
Am J Physiol Renal Physiol. 2012 Oct;303(7):F1099-106.

MYO1E Mutations and Childhood Familial Focal Segmental Glomerulosclerosis.
Mele C, Iatropoulos P, Donadelli R, Calabria A, Maranta R, Cassis P, Buelli S, Tomasoni S, Piras R, Krendel M, Bettoni S, Morigi M, Delledonne M, Pecoraro C, Abbate I, Capobianchi MR, Hildebrandt F, Otto E, Schaefer F, Macciardi F, Ozaltin F, Emre S, Ibsirlioglu T, Benigni A, Remuzzi G, Noris M. N Engl J Med. 2011 Jul 28;365(4):295-306.

Myo1e binds anionic phospholipids with high affinity.
E.A. Feeser, C.M. Ignacio, M. Krendel, and E.M. Ostap. Biochemistry, 49:9353-60, 2010.

Disruption of Myosin 1e promotes podocyte injury.
M. Krendel, S.V.Kim, T. Willinger, T. Wang, M. Kashgarian, R.A. Flavell, and M.S. Mooseker. JASN, 20:86-94, 2009.