Comprehensive Pain Management Center

photo of Upstate Bone and Joint Center
Comprehensive Pain Management Center
Upstate Bone and Joint Center
Map & directions
Suite 205
6620 Fly Road, East Syracuse, NY 13057
Phone: 315 464-4259
Fax: 315 464-9393
Office Hours: 8:00 am - 4:00 pm

The Comprehensive Pain Management Center was founded in 1977 to evaluate and treat patients who suffer from chronic, intractable pain resulting from benign or malignant disease.

P. Sebastian Thomas, MD

P. Sebastian Thomas, MD
Appointed 07/01/81
4702 Upstate University Hospital - Downtown Campus
750 East Adams Street
Syracuse, NY 13210

315 464-4891

Current Appointments

Hospital Campus

  • Downtown
  • Community

Clinical Section Affiliations

  • Anesthesiology: Pain Treatment


Education & Fellowships

  • Residency: Montefiore Hospital and Medical Center, 1980
  • MD: Gandhi Nagar Medical College, India, 1972

Clinical Interests

  • Reflex sympathetic dystrophy; low back pain

Research Interests

  • Low Back Pain; Discogenic Disease; Spinal Stenosis; Lumbar Radiculopathy; Reflex Sympathetic Dystrophy; Myofascial Pain Syndrome; Past Laminectomy Syndrome; Headaches; Facet disease; Fibromyalgia

Clinical Trials

  • The utility of Stellate Ganglion Blocks in patients with PTSD and Neuropathic pain
    Read more

Specialties & Certification

  • Anesthesiology
  • Chronic Pain Management


  • Adults and Children


  • Adult Anesthesiology
  • Chronic Pain Rehabilitation
  • Electrical Stimulation for Pain
  • Epidural/Caudal
  • Fluoroscopic Guided Precision Blocks
  • General Anesthesia for Bone Marrow Biopsy and Aspiration, and Spinal Tap Procedures
  • General Anesthesia for Dental Procedures
  • General Anesthesia for Radiographic Procedures (MRI, CT Scan, Interventional Radiology, Nuclear Medicine)
  • General Anesthesia for Surgical Procedures (General Surgery, ENT, Orthopedics, Vascular, Neurosurgery, and Others)
  • Intrathecal Pump Management
  • Intrathecal Pump Refill
  • Pain Control
  • Periphal blocks


  • American Society of Anesthesiologists
  • American Medical Association
  • New York State Society of Anesthesiologists (NYSSA)

Current Hospital Privileges

  • Upstate University Hospital
  • VA Medical Center

Languages Spoken (Other Than English)

  • Malayalam

Web Resources


Link to PubMed External Icon (Opens new window. Close the PubMed window to return to this page.)


Selected References

B.R. Krauss, A. Barbar, P.S. Thomas, A.V. Apkarian, Performance on a Decision-Making Task in Sympathetically Mediated Chronic Pain (RSD CRPS I) Patients: Evidence for Cognitive Impairment. 9th World Congress on Pain, August 22-27, 1999, Vienna, Austria

Willoughby PH, Thomas PS, Kamani V, Joy S. Epidural Blood Patch Performed on a 23 Month Old Male: A Case Report. 53rd Post Graduate Assembly, New York, New York, December 1999.

Igor D. Grachev, TS Ramachandran, Thomas, PS, NM Szeverenyi, BF Fredrickson: Association between dorsolateral prefrontal N-acetyl aspartate and depression in chronic back pain: An in vivo evidence for overlapping circuitries in the brain, Submitted for publication in Journal of Neural Transmission, January 18, 2002.

Thomas PS, Apkarian AV, Krauss BR, Szeverenyi NM: Differential effects of blocking chronic RSD pain on frontal and parietal cortical activations: an MRI study. Soc. Neurosci, Abstract. 21 (1995)

Thomas PS, Krauss BR, Apkarian AV, Szeverenyi NM: Sympathetically maintained chronic pain is a hyperfrontal condition. Soc. Neurosci Abst. 23 (1997)

Clinical Profile Shortcut:
Faculty Profile Shortcut:

In 1988, Upstate Comprehensive Pain Management Center was added to provide adequate analgesia for patients with post-surgical pain, post-traumatic pain, or acute exacerbation of chronic pain.

Since its inception, Upstate Comprehensive Pain Management Center has expanded both physically and in the scope of services provided. This expansion allows us to evaluate and treat patients in order to provide:

  • Prolonged, tolerable pain relief
  • Reduction of dependency on medications, particularly narcotics
  • Education of patients and family
  • More active and productive lives

Upstate Comprehensive Pain Management Center is the first comprehensive pain center in the central New York area, and it is one of only a few pain centers that offers integrated pain services for patients with acute and chronic pain syndromes. In order to meet patients' complex medical needs, the Center frequently draws upon other specialty medical services available at SUNY Upstate Medical University.

A variety of invasive and non-invasive treatments are utilized including

  • Differential Neural Blockade
  • Sympathetic and Steroid blocks
  • Regional infiltration of the muscle
  • Peripheral nerve blocks
  • Cryoanalgesia
  • Pharmacologic therapy
  • TENS/Interferential therapy
  • Psychological counseling
  • Implantation of dorsal column stimulators and intrathecal morphine pumps

In keeping with the Upstate Medical University's tradition, clinical research and education are ongoing and integral parts of Upstate Comprehensive Pain Management Center.

Some common syndromes seen at the center

  • Chronic Low back pain
  • Sympathetically mediated pain
  • Painful condition following any type of injury; usually presenting as severe burning pain, discoloration, and swelling
  • Post herpetic and Diabetic neuralgias
  • Pain following shingles and painful hands and feet associated with diabetes
  • Post operative neuralgias
  • Shooting type of pain associated with minor injury to nerve
  • Deafferentation pain—e.g., phantom limb pain
  • Cancer pain
  • Fibromyalgia—Painful conditions from muscles and ligaments